Prune is a 4-star Anemo character expected to arrive in Genshin Impact version 6.6 (Luna VII) alongside Nicole and Lohen. The good news for anyone planning to pull for her is that none of her ascension or talent level-up materials require the new weekly boss being introduced in 6.6 — meaning you can stockpile everything she needs well before the patch goes live.
Quick answer: Prune needs Vayuda Turquoise gems, 168 Winter Icelea, 46 Radiant Antler, Treasure Hoarder Insignias, Resistance talent books from Forsaken Rift, and 18 Mask of the Virtuous Doctor from the False Moon Institute Trounce Domain. All of these are farmable right now.

Prune's Full Ascension Materials (Level 1 → 90)
Reaching level 90 requires a standard set of character ascension resources. Prune uses Anemo-aligned gemstones, a Nod-Krai local specialty, an overworld boss drop, and common enemy materials from Treasure Hoarders.
| Material Type | Items Needed |
|---|---|
| Mora | 420,000 |
| Anemo Gemstones | 6 Vayuda Turquoise Sliver, 9 Vayuda Turquoise Fragment, 9 Vayuda Turquoise Chunk, 1 Vayuda Turquoise Gemstone |
| Local Specialty | 168 Winter Icelea |
| Boss Material | 46 Radiant Antler |
| Common Materials | 18 Treasure Hoarder Insignia, 30 Silver Raven Insignia, 36 Golden Raven Insignia |
Prune's Talent Level-Up Materials (Triple Crown)
Maxing all three talents to level 10 is a significantly larger investment than ascension alone. Prune draws from the Resistance book series out of Mondstadt and the Mask of the Virtuous Doctor weekly boss drop, which already exists in the game. The combined totals for all three talents are listed below.
| Material Type | Per Talent (to Lv. 10) | All 3 Talents |
|---|---|---|
| Mora | 1,625,500 | 4,957,500 |
| Teachings of Resistance | 3 | 9 |
| Guide to Resistance | 21 | 63 |
| Philosophies of Resistance | 38 | 114 |
| Treasure Hoarder Insignia | 6 | 18 |
| Silver Raven Insignia | 22 | 66 |
| Golden Raven Insignia | 31 | 93 |
| Mask of the Virtuous Doctor | 6 | 18 |
| Crown of Insight | 1 | 3 |

Combined Material Totals (Ascension + All Talents)
If you want the complete shopping list for taking Prune from level 1 to 90 with all three talents maxed, here are the combined numbers across both ascension and talent upgrades.
| Material | Total Needed |
|---|---|
| Mora | ~5,377,500 |
| Vayuda Turquoise Sliver | 6 (ascension only) |
| Vayuda Turquoise Fragment | 9 |
| Vayuda Turquoise Chunk | 9 |
| Vayuda Turquoise Gemstone | 1 |
| Winter Icelea | 168 |
| Radiant Antler | 46 |
| Treasure Hoarder Insignia | 36 |
| Silver Raven Insignia | 96 |
| Golden Raven Insignia | 129 |
| Teachings of Resistance | 9 |
| Guide to Resistance | 63 |
| Philosophies of Resistance | 114 |
| Mask of the Virtuous Doctor | 18 |
| Crown of Insight | 3 |
Where to Farm Each Material
Winter Icelea
Winter Icelea is a Nod-Krai local specialty found in the Voidsea Outlook and Wavechaser Plain areas. You need 168 of them, so plan on multiple collection runs with 48-hour respawn timers between each sweep. Marking routes on the in-game map or using the official interactive map helps speed this up considerably.

Radiant Antler
Radiant Antler drops from the Frostnight Herra, an overworld boss located on Hiisi Island in Nod-Krai. At 46 required drops and roughly 2–3 per kill, expect to spend around 15–23 boss runs' worth of Resin here. This boss is already available, so you can start immediately.
Vayuda Turquoise Gems
As Anemo character ascension stones, these drop from a wide range of bosses. The Anemo Hypostasis in Mondstadt is the fastest and most straightforward option. Other sources include the Maguu Kenki, Solitary Suanni, Setekh Wenut, Tenebrous Papilla, ASIMON, Icewind Suite: Coppelia, and the Stormterror and Joururi Workshop Trounce Domains. You can also convert other elemental gems using Dust of Azoth from the Paimon shop.

Treasure Hoarder / Silver Raven / Golden Raven Insignia
These common materials drop from Treasure Hoarder enemies scattered across Teyvat. You'll need a combined 261 Insignias across all rarities, which is a substantial amount. The Adventurer's Handbook can help you track Treasure Hoarder locations. Crafting lower-tier Insignias into higher-tier ones at the alchemy bench is also an option, though it's Mora-intensive. If you've been building other recent characters like Linnea or Durin, your stockpile may already be thin — Treasure Hoarder drops have become one of the most in-demand common materials in the 6.x patch cycle.
Resistance Talent Books
Teachings, Guide, and Philosophies of Resistance are farmed from the Forsaken Rift domain in Mondstadt. This domain is available on Tuesday, Friday, and Sunday. With 114 Philosophies needed for a triple crown, you'll want to start running this domain early and often. Condensed Resin can double your efficiency on farming days.
Mask of the Virtuous Doctor
This weekly boss material comes from the False Moon Institute Trounce Domain in Nod-Krai — the Dottore fight. You need 18 total for a triple crown, and weekly bosses drop roughly 2–3 of their materials per clear (with a chance at Dream Solvents to convert other drops). At best, that's around 6–9 weeks of weekly clears, so this will be the slowest bottleneck. The domain is already accessible, and you can quick-start it without completing the associated Archon Quest if you don't mind potential story spoilers.

A Quick Look at Prune's Leaked Kit
Understanding what Prune does in combat helps you decide which talents to prioritize. She's an Anemo support/sub-DPS built around Swirl reactions, using two signature tools: the Hunting Oath Hammer and the Lure Witch Bell.
Her Elemental Skill summons the hammer and strikes the bell, dealing Anemo DMG. If the hit triggers a Swirl, the skill upgrades for six seconds into Dongqiangqiang: Punishment of the Bane, which absorbs the Swirled element and converts the hammer's attacks into that element's damage type.
Her Elemental Burst shakes the bell, dealing AoE Anemo DMG and putting it into "Hunting Mode." While active, the bell follows the on-field character and periodically attacks nearby enemies with Anemo DMG counted as Burst damage. Her first passive talent (Severing Retribution) spawns additional elemental hammers when the bell Swirls in Hunting Mode, and her second passive (Resonant Bell) grants teammates a damage buff called "Ringing Inspiration" that scales off Prune's ATK above 1,000.
Her third passive, Witch's Eve: Oath of the Hunt, is a Hexerei team synergy talent. When two or more Hexerei characters are in the party, those affected by Ringing Inspiration gain 45% ATK after triggering an elemental reaction, with an extra 20% ATK bonus specifically for Swirl reactions. This makes Prune a strong pick in Hexerei compositions alongside characters like Nicole.
Her crafting passive gives a 10% chance to produce a bonus talent level-up material of the same region and rank when crafting at the alchemy bench.

Prune's Constellations
| Constellation | Effect |
|---|---|
| C1 | Transformed Hunting Oath Hammer hits regenerate 2 Energy for Prune (once per 1.8s). |
| C2 | After using Burst, Prune gains 10% ATK while the bell is in Hunting Mode. Hammer or bell hits grant an additional 5% ATK, stacking up to 40%. |
| C3 | Elemental Burst level +3. |
| C4 | Transformed hammer bounces once more on hit, dealing 80% of Prune's ATK as additional DMG to nearby enemies. |
| C5 | Elemental Skill level +3. |
| C6 | Hunting Mode duration extended by 4 seconds. When a character with Ringing Inspiration triggers an Elemental reaction, Prune and all other nearby Ringing Inspiration holders gain 350 ATK for 5 seconds. |
C2 and C6 are the standout constellations for players looking to maximize Prune's ATK-scaling support capabilities. C4 adds meaningful extra damage in AoE situations. As a 4-star, you'll likely pick up constellations naturally while pulling for the 5-star characters on her banner.
All of Prune's materials are already farmable in the current version of Genshin Impact. The weekly Mask of the Virtuous Doctor will be the longest grind due to the once-per-week lockout, so starting those clears now gives you the best head start. Everything else — Winter Icelea, Radiant Antler, Resistance books, and Treasure Hoarder Insignias — can be knocked out at your own pace before 6.6 arrives. Keep in mind that all leaked details remain subject to change before the official release.