Laudanum is a side quest in Chapter 7 of Valor Mortis, set in The Outskirts. An old woman behind a locked door on the Island of Whispers asks William to find medicine for the typhus-stricken children in her care. Her story does not hold up, and your answer to the children upstairs decides who walks out of that house alive.
Quick answer: Talk to the children through the upstairs door and agree to poison the laudanum before you pick up the bottle. That is the only route where the children survive.
Laudanum quest outcomes: poison or plain bottle
The old woman dies no matter what you do. What changes is the fate of the children she keeps locked upstairs. She is a drunk who hoards every bottle of laudanum people bring her and gives the children nothing.
| Choice | Old woman | Children | Final interaction |
|---|---|---|---|
| Poison the laudanum | Dies from the poison | Escape alive | Sick Child’s Diary, upstairs dorm |
| Deliver it untouched | Dies from drink | All die | Her body and diary, downstairs |
The decision is made at the children’s door, not at delivery. If you agree to help them, William mixes the rat poison in the instant he picks up the laudanum, and there is no way to back out afterward. If you decline, or never speak to the children at all, she gets a clean bottle. Her diary in that ending reveals she planned to lock up more children to keep the sympathy and the free medicine coming. Neither outcome changes the main story in later chapters.
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This quest becomes available in Chapter 7, Witch Hunt, as you make your way through The Outskirts. First, the children called the Mice must have spoken with you twice.


Agree to take the Poison-Filled Bottle, or refuse if you want to deliver a plain bottle.
Agreeing here is permanent. Once you accept the rat poison, every bottle of laudanum William picks up for this quest becomes Poisoned Laudanum.
Where to find the laudanum in Barnaby’s house
The bottle sits in Barnaby’s house, past the Market Square lantern. The road there runs through poison clouds and a few fights, so top up your flasks first.
After agreeing to help the children, you’ll see Poisoned Laudanum listed as the pickup. William applies the poison automatically, so no additional item or interaction is required.

Exit through the nearby door, then lower the wooden ramp to create a shortcut to the Market Square lantern. From that lantern, fast travel to the Island of Whispers.
Delivering the bottle and finishing Laudanum


You know it worked when the “QUEST COMPLETE” banner for Laudanum appears and The Bitter Cure achievement unlocks. In the poison ending, check the open back window with candles as well for a final journal update.
Laudanum rewards and item values
Finishing the quest grants the Potent Concoction amber. In the poison ending, the children leave William a Tiny Whisker Gift as thanks. The old woman hands over a Mythic Catalyst Clot when you deliver the bottle.
| Item | Type | Effect | Max carried / rank |
|---|---|---|---|
| Amber | Flask restores 20% / 30% / 40% Nephtoglobin | Max rank 3 | |
| Consumable | Grants 3000 Catalysts | 99 | |
| Consumable | Grants 2000 Catalysts | 99 |
Potent Concoction makes a Ferrofluid Flask refill Nephtoglobin on top of Health, by the rank percentages above. Copies of this amber also sit in chests in Valley of Ashes and the Fortress, and one of those chests is trapped.
Tiny Whisker Gift is a present from the Mice. It sells for 3000, the same amount it grants in Catalysts when used.
Mythic Catalyst Clot costs 4000 to buy and sells for 2000. It also turns up all over the map, with 4 in The Outskirts and 12 in the City of Orphans.
The Exquisite Firearm Parts in the barn on the way to Barnaby’s house are worth the detour. Pistol, Blunderbuss and Musket each need one part to reach level 8 and two more for level 9.
Laudanum is not missable. You can return to The Outskirts after the main story to start or finish it. Doing it during Chapter 7 still saves a trip, since both the Island of Whispers and Market Square sit right on your path to the Lighthouse.



