Climbing the Tower and Nature Tower leaderboards in Anime Story 2 comes down to one thing: stacking the highest-DPS carries behind a reliable tank, a damage-over-time support, and the right leader in slot one. The current meta rewards consistent damage that holds up as enemy waves scale, so the best teams lean on units that keep dealing damage every round instead of relying on luck.
Quick answer: For regular Tower, run Asota (Devil) as your leader, Kaizen (Ascended) and Slime (Demon) as carries, Raven (Red) as your tank, and a support like Joilios King. For Nature Tower, swap in Dark Swordsman (Ascended) as the main DPS and add Sound Breather Master, then equip Baseball Bat, Flame Sword, or Candy Cane on your damage units.

Best units for regular Tower
Regular Tower runs reward units that survive long stretches and keep their damage stable as difficulty spikes. The S-tier DPS units carry this mode because their passives boost damage automatically each round. Kaizen (Ascended) stands out because it stuns three enemies for one turn at the start of the round and deals 200% more damage on its first attack, which can save a run during dangerous waves.
| Unit | Role | Why it works in Tower |
|---|---|---|
| Kaizen (Ascended) | DPS | Stuns 3 enemies at round start, +200% on first attack |
| Slime (Demon) | DPS / Support | Buffs Water units +50%, all others +10%, applies Black Flames |
| Asota (Devil) | Leader / DPS | Immune to all crowd control, gains +25% damage per kill |
| Vampire Brandon | DPS | Very tanky with self-healing, applies Bleed to all enemies |
| Majestic Vampire | DPS | AoE damage with Crit stacking, freezes ground enemies every 3 turns |
Vampire Brandon is a strong pick for longer Tower attempts because his self-healing and high survivability keep him alive while he stacks Bleed. Reaper (Bankai) is a solid early-Tower option if you are still building your roster, though it needs strong stats to compete with the units above.

Best units for Nature Tower
Nature Tower puts a premium on raw, sustained DPS, and Dark Swordsman (Ascended) is the strongest carry for it right now. He applies Bleed for 80% of his damage as damage over time, and that Bleed doubles when enemies are already burning. He also dodges the first incoming attack and counters, which helps him stay alive deep into a run.
Sound Breather Master is the other key Nature Tower pick as the best pure DPS unit in the game. His damage is excellent in late-game content, and he gains +15% crit chance when Black Bull is on the team, so pairing those two creates a clear synergy. His Musical Score passive can swing high or low, but the ceiling is worth it for leaderboard pushes.
| Unit | Role | Key trait for Nature Tower |
|---|---|---|
| Dark Swordsman (Ascended) | DPS | Best Nature Tower carry, doubles Bleed on burning enemies |
| Sound Breather Master | DPS | Best pure DPS, +15% crit chance with Black Bull |
| Ant King | DPS / Support | Marks all enemies for +20% damage, 50% Poison chance |
| Slime (Demon) | DPS / Support | Element-wide damage buffs and Black Flames pressure |
Leader slot priority for Tower runs
The unit you place in slot one activates its leader skill and buffs the whole team, so this choice shapes your entire run. Asota (Devil) is the top leader because his skill gives all Sword allies +15% damage, and he is completely immune to Stun, Poison, Black Flames, Freeze, Burn, and Frostbite. He attacks twice on the first round, then gains +25% damage and heals all allies by 20% of their max health on every kill.
Flame Lion is the next-best leader when your team runs burn and flame damage. Her skill doubles burn and Black Flame damage for the whole team, and every attack she lands triggers a second flame hit. Pure damage amplification tends to beat health-based buffs in Tower because late waves can wipe a team quickly.

Best tanks and supports for the leaderboard
A leaderboard team needs one tank to absorb damage and a support to amplify your carries. Raven (Red) is the best tank in the game and the default front-line pick for protecting your DPS. Black Bull doubles as a tank and a synergy enabler since it boosts Sound Breather Master’s crit chance.
| Role | Top picks |
|---|---|
| Meta Tanks | Raven (Red), Black Bull, Titan, Ruki, Vogita |
| Meta Support | Joilios King, Yono Star, Destruction, Gojin, Tatsumaki |
For damage-over-time teams, a support that multiplies your Bleed and Poison effects is the fastest way to raise total damage. Pairing Shadow Knight, Ant King, and a DoT amplifier creates one of the most consistent damage chains, which is exactly what long Tower runs reward.
Best relics for Tower DPS units
Relics decide whether your carries hit their full potential. The S-tier DPS units all want the same short list of damage relics, so you can standardize your loadouts across Tower and Nature Tower.
- Baseball Bat — the default damage relic for nearly every meta DPS unit.
- Flame Sword — strong on units that already apply burn or Black Flames.
- Candy Cane — a reliable third option across the same carries.
Note: Majestic Vampire performs best with Baseball Bat specifically, so prioritize that relic on him before spreading the others around.

How to know your Tower team is leaderboard-ready
A finished team should clear deep Tower waves without losing a unit to crowd control or burst damage. If your run ends early, the cause is usually one of a few fixable problems. Check these before your next attempt.
- No leader in slot one — your team loses the full leader buff if the slot is filled by a non-leader unit.
- Missing tank — without Raven (Red) or another meta tank, your DPS units take direct hits and fall fast.
- Wrong relics — DPS units running off-meta relics deal far less damage than their ceiling.
- Broken synergy — Sound Breather Master without Black Bull, or a DoT carry without a damage-over-time support, leaves damage on the table.
Once your carries are equipped, your tank holds the front, and Asota (Devil) or Flame Lion sits in the leader slot, you have the framework that pushes Tower and Nature Tower scores into the top 10. Build around one strong leader, slot in a damage-over-time support, and let your S-tier DPS do the rest.






