Chapter 10-22 asks you to defeat Black Lotan inside the Peaceful Secret Lab, and the fight has a reputation for being a Legendary-gear wall. It isn’t. A fully built Epic-tier setup clears it, provided you respect the boss’s red ground markers and stop trying to trade hits with it.
Quick answer: Enter the Peaceful Secret Lab, clear the security robots, grab the security code and use the gate console to open the inner door, then kill Black Lotan by striking in short bursts and moving out of every red area indicator. Around 2,150 ATK, 2,130 DEF and roughly 134,000 Combat Power on Epic gear is enough.
Stat benchmark for clearing 10-22 on Epic gear
These are the numbers a clear was completed with, so treat them as a floor rather than a target you need to exceed. Nothing here is Legendary tier.
| Stat or loadout slot | Value at clear |
|---|---|
| Total ATK | 2,156 |
| Total DEF | 2,131 |
| Total ACC | 1,591 |
| Combat Power | 134,111 |
| Biosuit | Ferrum Exploder |
| Rover | Regulus |
| MAU | Lv. 4 Kraken |
| Launcher | Lv. 52 Chiron Laser Cannon |
Accuracy matters more than raw attack here. If your hits are landing but the damage feels slow, that is normal for this fight and not a sign you need better gear.
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Note: cutscenes and dialogue between these beats can be skipped with the SKIP prompt if you are running this a second time on another character.

Black Lotan fight: hit-and-run pattern
Black Lotan telegraphs almost everything with red area-of-effect markers on the floor. The entire fight comes down to reading those markers rather than out-gearing the boss, which is why an Epic setup works.
The quest tracker reads “10-22 Defeat Black Lotan 0/1” throughout, and flips over when the boss goes down.

How to confirm 10-22 is finished
Killing the boss is not the last beat. After the fight you check on Sitz Paro, then head for the exit while the HUD objective updates to “10-22 Exit the Complete” with a cyan waypoint pointing the way out.
Leaving the lab through that waypoint completes the Secret Space Discovery quest, which is your confirmation that the chapter step registered. If you defeated Black Lotan but the chapter has not advanced, you almost certainly have not walked out through the exit yet.

Cheap defense boost: the market gear swap
If your DEF is short of the benchmark, the market is usually faster than enhancing. Buying a higher-enhanced copy of a piece you already own and selling your old one back closes most of the gap for very little net spend.
| Transaction | Item | Price |
|---|---|---|
| Purchase | +9 Prime Cut-Resistant Neck Guard | 3,500 |
| Sale | +6 Prime Cut-Resistant Neck Guard | 2,099 |
| Net cost | Three enhancement levels | 1,401 |
The same logic applies to any defensive slot where the price gap between enhancement tiers is small. Check both sides of the trade before you buy, since the sale value of your current piece is what makes the swap worth doing.
Collection bonuses worth checking before the run
Active Collection sets feed directly into your combat stats, and event categories are easy to leave unclaimed. Open the Collection menu and work through the Event tab before you enter the lab, since anything sitting there uncollected is free stat weight you are not using in the fight.

Chapter 10 pushes the story into the frozen region of Severia, and later steps get harder than 10-22. Getting through the Black Lotan fight on Epic gear is a useful gauge, because if you can hold the hit-and-run pattern here without dying, your gear is not the thing holding you back further into the chapter.






